Best Supplements for Hormonal Balance in 2025 (Backed by Science)

Fact-Checked By a Nutritionist MD

Published on October 9, 2025

Your hormones control everything — from your energy and mood to sleep, focus, and metabolism. When they’re balanced, you feel calm, clear, and energised. But when they’re off, fatigue, brain fog, and mood swings can creep in.

 

If you’ve been feeling out of rhythm, the right nutritional support can make a real difference. Here are the best supplements for hormonal balance in 2025, starting with the one that supports your body from every angle — the brain, body, and biome.

What Are Hormones — and Why Do They Matter?

Hormones are your body’s internal messengers — controlling energy, mood, metabolism, sleep, and stress. When balanced, they keep everything running smoothly. When disrupted, you might feel tired, moody, or out of sync.

 

Modern stress, poor diet, and gut imbalance can all throw hormones off track. The key isn’t to “fix” one hormone but to support the foundations that regulate them — your brain, body, and biome.

 

That’s where the right supplements come in. Below are the best supplements for hormonal balance in 2025, starting with one that supports all three systems in harmony.

✅ 1. GRNS — Hormonal Balance from the Inside Out

When it comes to supporting hormones naturally, GRNS takes a foundational approach. Instead of targeting one hormone, it nourishes the systems that control them — your gut, stress response, and cellular energy.

 

Why It Helps:

Balances stress hormones: Adaptogens like Ashwagandha and Rhodiola help regulate cortisol, supporting calmer moods and better focus.

Supports estrogen metabolism: Prebiotics, probiotics, and fibre feed the gut microbiome — crucial for clearing excess estrogen and maintaining balance.

Reduces inflammation: Antioxidant-rich greens like spirulina and chlorella calm the internal stress that disrupts hormone production.

Boosts nutrient availability: Essential vitamins and minerals, including B vitamins and magnesium, help your body create and regulate hormones efficiently.

 

Why It’s Different:

GRNS isn’t just another greens blend — it’s built to strengthen the connection between your brain, body, and biome, giving your hormones the stable environment they need to stay in sync.

2. Ashwagandha Supplements

Ashwagandha is one of the most researched adaptogens, known for its ability to lower cortisol levels and improve resilience to stress.

 

Benefits:

- Reduces cortisol spikes and anxiety

- Supports thyroid function

- Improves sleep and mood stability

 

How to use: 300–600 mg daily of a high-quality extract such as KSM-66 or Sensoril.

3. Magnesium Supplements

Magnesium supports over 300 biochemical reactions in the body, including those involved in hormone synthesis and nervous system regulation.

 

Benefits:

- Calms the nervous system and improves sleep

- Supports progesterone and estrogen balance

- Reduces PMS and cramping

 

Best forms: Magnesium glycinate or citrate for better absorption.

🦠 4. Probiotics

Your gut microbiome directly affects hormone metabolism. A diverse gut flora helps your body eliminate excess estrogen and balance cortisol levels.

 

Benefits:

- Supports digestion and estrogen clearance

- Reduces bloating and fatigue

- Improves mental clarity via the gut-brain axis

 

Tip: Look for strains like Lactobacillus Rhamnosus and Bifidobacterium Bifidum — both are included in GRNS.

🐟 5. Omega-3 Supplements

Omega-3s are essential fats that help reduce inflammation and support hormone production. They’re especially beneficial for women’s health and thyroid function.

 

Benefits:

- Supports mood and brain health

- Improves insulin sensitivity

- Helps maintain menstrual balance

 

Sources: Fish oil, algae oil, or flaxseed oil supplements.

🥦 6. Cruciferous Vegetables & DIM

Compounds in broccoli, kale, and Brussels sprouts — especially DIM (Diindolylmethane) — help your liver metabolise excess estrogen and maintain hormonal equilibrium.

 

Benefits:

- Reduces symptoms of estrogen dominance

- Supports clear skin and mood stability

- Promotes healthy detoxification pathways

 

Tip: A greens powder rich in cruciferous compounds (like GRNS) offers these benefits in one simple scoop.

🧘‍♀️ 7. B Vitamin Supplements

The B-vitamin family (B6, B9, B12) plays a major role in energy metabolism, neurotransmitter production, and hormone balance.

 

Benefits:

- Supports mood and reduces fatigue

- Regulates menstrual and adrenal hormones

- Essential for thyroid and brain function

 

Best sources: Leafy greens, legumes, whole grains — or a supplement blend that includes B-complex vitamins naturally (like GRNS).

The Bottom Line

Hormonal balance doesn’t come from one pill or powder — it’s about supporting your foundations. When your brain, body, and biome are nourished, your hormones naturally find their rhythm again.

 

If you’re looking for a place to start, GRNS offers a complete, clean, and science-backed way to nourish your body daily. It helps regulate stress, support gut health, and maintain energy — all key to hormonal harmony.

🌿 FAQs About Hormonal Balance and Supplements

1. Can greens powders really help balance hormones?

Greens powders don’t directly change your hormones — they support the systems that regulate them. By improving gut health, reducing inflammation, and providing nutrients that influence stress and energy, they create the internal balance your hormones need to function properly.

 

2. Which nutrients are most important for hormonal health?

Key nutrients include magnesium, B vitamins, omega-3s, and adaptogens like Ashwagandha and Rhodiola. These help regulate cortisol, support thyroid function, and aid in estrogen metabolism — all essential for hormonal balance.

 

3. How long does it take to notice results?

While energy and digestion can improve within a few weeks, deeper hormonal changes take time. Most people notice meaningful shifts in mood, energy, and cycle regularity after 6–12 weeks of consistent, nutrient-rich support.

 

4. Can men benefit from hormonal balance supplements too?

Absolutely. Hormonal balance isn’t just a women’s health topic. Men also experience fluctuations in cortisol, testosterone, and insulin. Supporting gut health, nutrient absorption, and stress regulation benefits everyone.

 

5. What makes GRNS a good choice for hormone support?

GRNS combines adaptogens, probiotics, antioxidants, and natural greens to support the entire brain–body–biome network. It helps stabilise stress hormones, enhance gut balance, and reduce inflammation — creating the foundation for long-term hormonal harmony.

Simply, All in One.

  • 40+ Superfoods & Greens

  • Gut & Hormone Support

  • No Nasties

  • Advanced Foundational Support

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 *The statements have not been evaluated by the TGA / Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Information on this site is provided for informational purposes only. It is not meant to substitute for medical advice from your physician or other medical professional. You should not use the information contained herein for diagnosing or treating a health problem or disease, or prescribing any medication. Carefully read all product documentation. If you have or suspect that you have a medical problem, promptly contact your regular health care provider.

 

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